What is Lewy Body?
Classically, when we look down the microscope at someone who has Parkinson’s disease and look at their brain, we can see...
What is Vascular Dementia?
Vascular Dementia often comes into our thinking when we’re looking at some patients with dementia. And what we’re seeing with Vascular...
What is Frontotemporal Dementia?
Frontotemporal Dementia is probably one of the leading causes of younger onset dementia. Patients being affected from their 30s to their...
What is Lewy Body Dementia?
- September 7, 2017
- JP
- DementiaParkinson's and Mimics
People often confuse, and come up to me and ask what’s the difference between having Parkinson’s Disease or Lewy Body Dementia....
Sundowning in Alzheimer’s Disease
Sleep-wake disturbances are common in Alzheimer’s disease and can lead to great distress. The most frequently seen phenomenon is sundowning where...
The Role of Genes in Alzheimer’s Disease
The genetics of Alzheimer’s disease are a little bit more complicated. Unfortunately, we don’t see a very clear pattern in Alzheimer’s...
What is Progressive Supranuclear Palsy?
- September 8, 2017
- JP
- Parkinson's and Mimics
Progressive Supranuclear Palsy is a Parkinson mimic. To look alike, either in a typical Parkinson or a Parkinson Plus syndrome. So...
A Negative Reaction to the Diagnosis
- September 8, 2017
- JP
- DementiaParkinson's and Mimics
One of the challenges with these diseases of the brain, is that there can be a bit of a stigma attached...
Acetylcholine – an important brain chemical in memory function
Treating Alzheimer’s Disease is very challenging. Unfortunately, we don’t have very effective therapies that improve memory, but the strategies that we...
Device Assisted Technologies for the Advanced Therapy of PD
- September 8, 2017
- JP
- Parkinson's and Mimics
We talked a bit about the medications for Parkinson’s disease and how effective they are. Patients often say to me “Will...
Neurodegenerative Disease – Genes
- September 8, 2017
- JP
- DementiaParkinson's and Mimics
Probably the most common question I get asked by support groups and people in general is “Is this disease of mine...
Treatment for Atypical Parkinson’s Disease
- September 8, 2017
- JP
- Parkinson's and Mimics
Our treatment for atypical Parkinson’s Disease, Progressive Supranuclear Palsy, Multiple System Atrophy, Corticobasal Syndrome, Vascular Parkinsonism is much harder. In these...
Dopamine Agonists
- September 8, 2017
- JP
- Parkinson's and Mimics
One of our strategies for treating Parkinson’s disease is to trick the brain by giving patients a dopamine agonist, and dopamine...
COMT Inhibitors for the Treatment of Parkinson’s
- September 8, 2017
- JP
- Parkinson's and Mimics
In more advanced cases of PD, what we’d really like is for the dopamine to hang around for a bit longer,...
MAOB Inhibitors for the Treatment of Parkinson’s
- September 8, 2017
- JP
- Parkinson's and Mimics
One of the other strategies that we have that can treat Parkinson’s disease is to allow the dopamine that’s in the...
Challenges of Frontotemporal Dementia
Frontotemporal Dementia is a real challenge. The memory problems that we see with this dementia, don’t really respond to the treatments...
The Role of Genes in Frontotemporal Dementia
The genetics of Frontotemporal Dementia probably one of the most rapidly evolving fields that we have in this space. Probably 10...
The Immune System and Cell Death
- September 8, 2017
- JP
- DementiaParkinson's and Mimics
One of the things we see in degenerative diseases of the brain is the idea of inflammation or the immune system...
The Role of Proteins in Brain Disease
- September 7, 2017
- JP
- DementiaParkinson's and Mimics
We know that most of the diseases of the brain that we’re seeing that are degenerative, seem to be associated with...
The Research Clinic
All of the work I conduct relies on the good will of patients participating in the clinic. Here we can collect...
