Advanced Therapy for Parkinson's Disease

Device Assisted Technologies for the Advanced Therapy of PD

We talked a bit about the medications for Parkinson’s disease and how effective they are. Patients often say to me “Will...

Neurodegenerative Disease - Causes - Genes

Neurodegenerative Disease – Genes

Probably the most common question I get asked by support groups and people in general is “Is this disease of mine...

Treatment for Atypical Parkinson's Disease

Treatment for Atypical Parkinson’s Disease

Our treatment for atypical Parkinson’s Disease, Progressive Supranuclear Palsy, Multiple System Atrophy, Corticobasal Syndrome, Vascular Parkinsonism is much harder. In these...

Dopamine Agonist

Dopamine Agonists

One of our strategies for treating Parkinson’s disease is to trick the brain by giving patients a dopamine agonist, and dopamine...

dopamine-catechol-inhibitors

COMT Inhibitors for the Treatment of Parkinson’s

In more advanced cases of PD, what we’d really like is for the dopamine to hang around for a bit longer,...

dopamine-inhibitors

MAOB Inhibitors for the Treatment of Parkinson’s

One of the other strategies that we have that can treat Parkinson’s disease is to allow the dopamine that’s in the...

Challenges of Frontotemporal Dementia

Challenges of Frontotemporal Dementia

Frontotemporal Dementia is a real challenge. The memory problems that we see with this dementia, don’t really respond to the treatments...

The genetics of frontotemporal dementia

The Role of Genes in Frontotemporal Dementia

The genetics of Frontotemporal Dementia probably one of the most rapidly evolving fields that we have in this space. Probably 10...

Immune System and Cell Death

The Immune System and Cell Death

One of the things we see in degenerative diseases of the brain is the idea of inflammation or the immune system...

Proteins, Parkinson's, Alzheimer's, Dementia

The Role of Proteins in Brain Disease

We know that most of the diseases of the brain that we’re seeing that are degenerative, seem to be associated with...

The Research Clinic

All of the work I conduct relies on the good will of patients participating in the clinic. Here we can collect...

Genetics and Biomarkers Research

Understanding many of the degenerative diseases of the brain has led people to look at genetics and biomarkers. Where genes go...

Understanding the difference – Heterogeneity Research

Many people will have recognised that patients with the same diseases can look different. For example, in Parkinson’s not every patient...

Sleep Research

Problems of sleep and wakefulness cause significant problems and my team have been very active in this important field. Hopefully our...

Dementia Research

Dementia and cognitive decline cause significant problems that can trigger transition to nursing home care. My team have been very active...

Hallucinations Research

Hallucinations and other psychotic symptoms cause significant problems that can trigger transition to nursing home care. My team have been very...

Freezing of Gait Research

Freezing of Gait causes significant problems with mobility and often falls that can trigger transition to nursing home care. My team...

Is CURE a four letter word in Parkinson’s

Prof Simon Lewis explains the current approaches that people are taking in the pursuit of a cure. Australia is opening trials...

Clinical Trials Research

We are entering a phase of more active clinical trials for neurodegenerative conditions like Parkinson’s, Alzheimer’s and other dementias. Some of...

Slowing Cell Death

What other approaches do we have for slowing cell death? Well we know that a number of the diseases there seems...