
A Negative Reaction to the Diagnosis
- September 8, 2017
- JP
- DementiaParkinson's and Mimics
One of the challenges with these diseases of the brain, is that there can be a bit of a stigma attached...

Acetylcholine – an important brain chemical in memory function
Treating Alzheimer’s Disease is very challenging. Unfortunately, we don’t have very effective therapies that improve memory, but the strategies that we...

Device Assisted Technologies for the Advanced Therapy of PD
- September 8, 2017
- JP
- Parkinson's and Mimics
We talked a bit about the medications for Parkinson’s disease and how effective they are. Patients often say to me “Will...

Neurodegenerative Disease – Genes
- September 8, 2017
- JP
- DementiaParkinson's and Mimics
Probably the most common question I get asked by support groups and people in general is “Is this disease of mine...

Treatment for Atypical Parkinson’s Disease
- September 8, 2017
- JP
- Parkinson's and Mimics
Our treatment for atypical Parkinson’s Disease, Progressive Supranuclear Palsy, Multiple System Atrophy, Corticobasal Syndrome, Vascular Parkinsonism is much harder. In these...

Dopamine Agonists
- September 8, 2017
- JP
- Parkinson's and Mimics
One of our strategies for treating Parkinson’s disease is to trick the brain by giving patients a dopamine agonist, and dopamine...

COMT Inhibitors for the Treatment of Parkinson’s
- September 8, 2017
- JP
- Parkinson's and Mimics
In more advanced cases of PD, what we’d really like is for the dopamine to hang around for a bit longer,...

MAOB Inhibitors for the Treatment of Parkinson’s
- September 8, 2017
- JP
- Parkinson's and Mimics
One of the other strategies that we have that can treat Parkinson’s disease is to allow the dopamine that’s in the...

Challenges of Frontotemporal Dementia
Frontotemporal Dementia is a real challenge. The memory problems that we see with this dementia, don’t really respond to the treatments...

The Role of Genes in Frontotemporal Dementia
The genetics of Frontotemporal Dementia probably one of the most rapidly evolving fields that we have in this space. Probably 10...

The Immune System and Cell Death
- September 8, 2017
- JP
- DementiaParkinson's and Mimics
One of the things we see in degenerative diseases of the brain is the idea of inflammation or the immune system...

The Role of Proteins in Brain Disease
- September 7, 2017
- JP
- DementiaParkinson's and Mimics
We know that most of the diseases of the brain that we’re seeing that are degenerative, seem to be associated with...

The Research Clinic
All of the work I conduct relies on the good will of patients participating in the clinic. Here we can collect...

Genetics and Biomarkers Research
Understanding many of the degenerative diseases of the brain has led people to look at genetics and biomarkers. Where genes go...

Understanding the difference – Heterogeneity Research
Many people will have recognised that patients with the same diseases can look different. For example, in Parkinson’s not every patient...

Sleep Research
Problems of sleep and wakefulness cause significant problems and my team have been very active in this important field. Hopefully our...

Dementia Research
Dementia and cognitive decline cause significant problems that can trigger transition to nursing home care. My team have been very active...

Hallucinations Research
Hallucinations and other psychotic symptoms cause significant problems that can trigger transition to nursing home care. My team have been very...

Freezing of Gait Research
Freezing of Gait causes significant problems with mobility and often falls that can trigger transition to nursing home care. My team...

Is CURE a four letter word in Parkinson’s
- May 20, 2018
- JP
- Latest Research
Prof Simon Lewis explains the current approaches that people are taking in the pursuit of a cure. Australia is opening trials...