As a neurologist, I lobby, research, listen and learn to improve the lives of people living with Parkinson’s Disease, Dementia and Alzheimer’s. This website is devoted to helping those with a neurodegenerative disease sustain a quality of life and to gain trusted knowledge about their condition.

Welcome to the Video Library

View Videos on Parkinson’s & Mimics

Non-Motor Symptoms

Watch Prof Simon Lewis giving an overview on the Non-Motor Symptoms of Parkinson’s Disease to the Parkinson’s Support Group in Kiama,...

Sublingual Apomorphine

Watch Prof Simon Lewis explaining sublingual apomorphine as a recently approved treatment to rescue Parkinson’s patients from periods of Wearing Off....

PASADENA Prasinezumab 12 month data

Prof Simon Lewis describes the press release reporting the 12 month data of the PASADENA study evaluating prasinezumab, a novel monoclonal...

COVID-19

April 23, 2020
JP
DementiaLatest ResearchParkinson's and Mimics

Prof Simon Lewis delivers an overview on the impact of the COVID-19, coronavirus pandemic in relation to diseases like Parkinson’s and...

Novel treatments for Alzheimer’s

October 25, 2018
JP
DementiaLatest Research

Research is identifying the key factors that are driving Alzheimer’s and this is certainly offering more hope for developing effective treatments....

Modifiable Risk Factors for Dementia

October 25, 2018
JP
DementiaLatest Research

Whilst the number of people with Dementia is rising worldwide this may not be the whole story. Research is identifying that...

View Videos on Latest Research

Australian Parkinson’s Mission Channel 9 News

April 29, 2025
Simon Lewis
Latest Research

In a recent Channel 9 news feature, health correspondent Gabriella Rogers reported on a groundbreaking milestone in Australian neuroscience research—the completion...

Public Forum April 2025 Simon Lewis Research Overview

April 29, 2025
Simon Lewis
Latest Research

In the April Public Forum, attendees were welcomed by Professor Simon Lewis, a world-renowned neurologist and clinical researcher based at Macquarie...

Public Forum April 2025 Professor Roger Barker

April 29, 2025
Simon Lewis
Latest Research

Over the last 25 years our understanding of Parkinson’s disease (PD) has changed dramatically. This includes better understanding different types of...

Ongoing Research

To progress our understanding of neurodegenerative conditions, the research team led by Prof Simon Lewis has won a number of grants and awards from a range of sources including the National Health and Medical Research Centre (NHMRC) of Australia, the Australian Research Council, the Michael J Fox Foundation, as well as the University of Sydney itself, which funds promising projects under its Sydney Research Excellence Initiative 2020 (SREI 2020).

These research projects cover many different areas including trying to develop diagnostic blood tests, better understanding and management of specific symptoms such as gait disturbance, memory problems, hallucinations and sleep problems, as well trying to predict who will develop neurodegenerative diseases to allow treatment at the earliest possible stage.

This latter project specifically focuses on sleep and circadian disruption and its significance in the development of brain disorders. This project has led to the creation of an internationally renowned team of experts who are using novel approaches to study enriched cohorts of individuals who have been identified as having specific risk factors associated with the development of Dementia and Parkinson’s disease.

Capitalising on the clinical practice of Prof Simon Lewis within a research centre has enabled the team to recruit volunteers to undergo extensive testing at regular intervals. Through this approach the team will be able to evaluate the ability of biological markers to predict the emergence of brain disease.

About my Work

When I initially undertook my research at the University of Cambridge, UK, I became passionate about changing the lives of people living with neurodegenerative brain disease. Seeing the difficulties experienced by patients and their families led me to specialise in this field and I remain committed to making a difference. You could say that I am passionate about this, some might argue obsessed.

To hopefully help as many people as possible, I’ve created this website to summarise information about these conditions in a series of short, easily understood videos.

The video library will be updated regularly to keep pace with recent findings and research in these areas.

I am a NHMRC Practitioner Fellow working as a Consultant Neurologist at the Royal Prince Alfred Hospital and as Professor in Cognitive Neuroscience at the University of Sydney. I am also the Director of the Parkinson’s Disease Research Clinic at the Brain and Mind Centre and lead the NSW Movement Disorders Brain Donor program.

As a specialist neurologist I am interested in newly diagnosed and advanced Parkinson’s Disease and other neurodegenerative diseases, with expertise in freezing of gait, hallucinations, memory problems and sleep disturbances.